Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis

We report a case of a 46-year-old Vietnamese man who developed widespread, numerous and concurrent cutaneous squamous cell carcinomas (SCCs) in non-sun exposed skin areas after taking a traditional medicine (TM) formulation for chronic plaque psoriasis. The SCC lesions began to develop within 12–15...

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Autores principales: Siefring, Mark Louis, Lu, Doanh, States, J Christopher, Van Hoang, Minh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Reminder of Important Clinical Lesson
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884260/
https://www.ncbi.nlm.nih.gov/pubmed/29602886
http://dx.doi.org/10.1136/bcr-2017-222645
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author Siefring, Mark Louis
Lu, Doanh
States, J Christopher
Van Hoang, Minh
author_facet Siefring, Mark Louis
Lu, Doanh
States, J Christopher
Van Hoang, Minh
author_sort Siefring, Mark Louis
collection PubMed
description We report a case of a 46-year-old Vietnamese man who developed widespread, numerous and concurrent cutaneous squamous cell carcinomas (SCCs) in non-sun exposed skin areas after taking a traditional medicine (TM) formulation for chronic plaque psoriasis. The SCC lesions began to develop within 12–15 months after beginning the arsenic-containing TM. The patient experienced both acute and chronic symptoms consistent with arsenic exposure. Laboratory investigation of a collected hair sample showed a significant arsenic level. The TM formulation used by the patient was tested and demonstrated an extremely high concentration of arsenic.
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spelling pubmed-58842602018-04-06 Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis Siefring, Mark Louis Lu, Doanh States, J Christopher Van Hoang, Minh BMJ Case Rep Reminder of Important Clinical Lesson We report a case of a 46-year-old Vietnamese man who developed widespread, numerous and concurrent cutaneous squamous cell carcinomas (SCCs) in non-sun exposed skin areas after taking a traditional medicine (TM) formulation for chronic plaque psoriasis. The SCC lesions began to develop within 12–15 months after beginning the arsenic-containing TM. The patient experienced both acute and chronic symptoms consistent with arsenic exposure. Laboratory investigation of a collected hair sample showed a significant arsenic level. The TM formulation used by the patient was tested and demonstrated an extremely high concentration of arsenic. BMJ Publishing Group 2018-03-30 /pmc/articles/PMC5884260/ /pubmed/29602886 http://dx.doi.org/10.1136/bcr-2017-222645 Text en © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Reminder of Important Clinical Lesson
Siefring, Mark Louis
Lu, Doanh
States, J Christopher
Van Hoang, Minh
Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis
title Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis
title_full Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis
title_fullStr Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis
title_full_unstemmed Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis
title_short Rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis
title_sort rapid onset of multiple concurrent squamous cell carcinomas associated with the use of an arsenic-containing traditional medicine for chronic plaque psoriasis
topic Reminder of Important Clinical Lesson
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884260/
https://www.ncbi.nlm.nih.gov/pubmed/29602886
http://dx.doi.org/10.1136/bcr-2017-222645
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