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Sensitive Detection of the Natural Killer Cell-Mediated Cytotoxicity of Anti-CD20 Antibodies and Its Impairment by B-Cell Receptor Pathway Inhibitors

The antibody-dependent cell-mediated cytotoxicity (ADCC) of the anti-CD20 monoclonal antibodies (mAbs) rituximab and obinutuzumab against the cell line Raji and isolated CLL cells and its potential impairment by kinase inhibitors (KI) was determined via lactate dehydrogenase release or calcein reten...

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Detalles Bibliográficos
Autores principales:	Hassenrück, Floyd, Knödgen, Eva, Göckeritz, Elisa, Midda, Safi Hasan, Vondey, Verena, Neumann, Lars, Herter, Sylvia, Klein, Christian, Hallek, Michael, Krause, Günter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884282/ https://www.ncbi.nlm.nih.gov/pubmed/29750146 http://dx.doi.org/10.1155/2018/1023490

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