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Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node
Spontaneous regression of cancer is defined as disappearance of cancer in the absence of specific therapy. In thyroid cancer patients with biochemically incomplete response to initial treatments, spontaneous decline in thyroglobulin levels without any cancer treatment is a well-known phenomenon; how...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884408/ https://www.ncbi.nlm.nih.gov/pubmed/29755799 http://dx.doi.org/10.1155/2018/5873897 |
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author | Shim, Jien Rao, Jianyu Yu, Run |
author_facet | Shim, Jien Rao, Jianyu Yu, Run |
author_sort | Shim, Jien |
collection | PubMed |
description | Spontaneous regression of cancer is defined as disappearance of cancer in the absence of specific therapy. In thyroid cancer patients with biochemically incomplete response to initial treatments, spontaneous decline in thyroglobulin levels without any cancer treatment is a well-known phenomenon; however, spontaneous regression of persistent or recurrent structural disease has not been reported. We here present a case of papillary thyroid cancer in a 58-year-old female who underwent total thyroidectomy and two radioiodine ablations. She had persistently elevated thyroglobulin levels. Six years after her initial treatments, she had biopsy-proven cervical lymph node metastasis. The patient opted not to undergo any further treatment. Over the course of the next 10 years, without any additional treatment, the lymph node disappeared and her thyroglobulin levels decreased to almost undetectable ranges, implying near-complete regression. Our case illustrates that metastatic papillary thyroid cancer in lymph nodes can regress spontaneously. |
format | Online Article Text |
id | pubmed-5884408 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-58844082018-05-13 Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node Shim, Jien Rao, Jianyu Yu, Run Case Rep Endocrinol Case Report Spontaneous regression of cancer is defined as disappearance of cancer in the absence of specific therapy. In thyroid cancer patients with biochemically incomplete response to initial treatments, spontaneous decline in thyroglobulin levels without any cancer treatment is a well-known phenomenon; however, spontaneous regression of persistent or recurrent structural disease has not been reported. We here present a case of papillary thyroid cancer in a 58-year-old female who underwent total thyroidectomy and two radioiodine ablations. She had persistently elevated thyroglobulin levels. Six years after her initial treatments, she had biopsy-proven cervical lymph node metastasis. The patient opted not to undergo any further treatment. Over the course of the next 10 years, without any additional treatment, the lymph node disappeared and her thyroglobulin levels decreased to almost undetectable ranges, implying near-complete regression. Our case illustrates that metastatic papillary thyroid cancer in lymph nodes can regress spontaneously. Hindawi 2018-03-20 /pmc/articles/PMC5884408/ /pubmed/29755799 http://dx.doi.org/10.1155/2018/5873897 Text en Copyright © 2018 Jien Shim et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Shim, Jien Rao, Jianyu Yu, Run Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
title | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
title_full | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
title_fullStr | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
title_full_unstemmed | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
title_short | Spontaneous Regression of Metastatic Papillary Thyroid Cancer in a Lymph Node |
title_sort | spontaneous regression of metastatic papillary thyroid cancer in a lymph node |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884408/ https://www.ncbi.nlm.nih.gov/pubmed/29755799 http://dx.doi.org/10.1155/2018/5873897 |
work_keys_str_mv | AT shimjien spontaneousregressionofmetastaticpapillarythyroidcancerinalymphnode AT raojianyu spontaneousregressionofmetastaticpapillarythyroidcancerinalymphnode AT yurun spontaneousregressionofmetastaticpapillarythyroidcancerinalymphnode |