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An immuno-assay to quantify influenza virus hemagglutinin with correctly folded stalk domains in vaccine preparations

The standard method to quantify the hemagglutinin content of influenza virus vaccines is the single radial immunodiffusion assay. This assay primarily relies on polyclonal antibodies against the head domain of the influenza virus hemagglutinin, which is the main target antigen of influenza virus vac...

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Detalles Bibliográficos
Autores principales: Rajendran, Madhusudan, Sun, Weina, Comella, Phillip, Nachbagauer, Raffael, Wohlbold, Teddy John, Amanat, Fatima, Kirkpatrick, Ericka, Palese, Peter, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884525/
https://www.ncbi.nlm.nih.gov/pubmed/29617394
http://dx.doi.org/10.1371/journal.pone.0194830