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An immuno-assay to quantify influenza virus hemagglutinin with correctly folded stalk domains in vaccine preparations
The standard method to quantify the hemagglutinin content of influenza virus vaccines is the single radial immunodiffusion assay. This assay primarily relies on polyclonal antibodies against the head domain of the influenza virus hemagglutinin, which is the main target antigen of influenza virus vac...
Autores principales: | Rajendran, Madhusudan, Sun, Weina, Comella, Phillip, Nachbagauer, Raffael, Wohlbold, Teddy John, Amanat, Fatima, Kirkpatrick, Ericka, Palese, Peter, Krammer, Florian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884525/ https://www.ncbi.nlm.nih.gov/pubmed/29617394 http://dx.doi.org/10.1371/journal.pone.0194830 |
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