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Replication-incompetent gammaretroviral and lentiviral vector-based insertional mutagenesis screens identify prostate cancer progression genes

Replication-incompetent gammaretroviral (γRV) and lentiviral (LV) vectors have both been used in insertional mutagenesis screens to identify cancer drivers. In this approach the vectors stably integrate in the host cell genome and induce cancers by dysregulating nearby genes. The cells that contain...

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Detalles Bibliográficos
Autores principales:	Bii, Victor M., Collins, Casey P., Hocum, Jonah D., Trobridge, Grant D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper: Chromosome
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884640/ https://www.ncbi.nlm.nih.gov/pubmed/29643985 http://dx.doi.org/10.18632/oncotarget.24503

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