Cargando…
Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways
Glucose-regulated protein 78 (GRP78), an ER chaperone, is overexpressed in cancer cells. Solid tumor cells can secrete GRP78 that can promote tumor angiogenesis, differentiation of bone marrow-derived mesenchymal stem cells, tumor cell proliferation and polarization of tumor-associated macrophages....
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884641/ https://www.ncbi.nlm.nih.gov/pubmed/29643986 http://dx.doi.org/10.18632/oncotarget.24090 |