Selective lysis of breast carcinomas by simultaneous stimulation of sodium channels and blockade of sodium pumps

Sodium influx through voltage-gated sodium channels (VGSCs) coupled with balanced removal of sodium ions via Na(+), K(+)-ATPase is a major determinant of cellular homeostasis and intracellular ionic concentration. Interestingly, many metastatic carcinomas express high levels of these channels. We hy...

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Detalles Bibliográficos
Autores principales: Gould, Harry J., Norleans, Jack, Ward, T. David, Reid, Chasiti, Paul, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884651/
https://www.ncbi.nlm.nih.gov/pubmed/29643996
http://dx.doi.org/10.18632/oncotarget.24581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884651/
https://www.ncbi.nlm.nih.gov/pubmed/29643996
http://dx.doi.org/10.18632/oncotarget.24581

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