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Selective lysis of breast carcinomas by simultaneous stimulation of sodium channels and blockade of sodium pumps
Sodium influx through voltage-gated sodium channels (VGSCs) coupled with balanced removal of sodium ions via Na(+), K(+)-ATPase is a major determinant of cellular homeostasis and intracellular ionic concentration. Interestingly, many metastatic carcinomas express high levels of these channels. We hy...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884651/ https://www.ncbi.nlm.nih.gov/pubmed/29643996 http://dx.doi.org/10.18632/oncotarget.24581 |