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Pomalidomide enhanced gemcitabine and nab-paclitaxel on pancreatic cancer both in vitro and in vivo
BACKGROUND: Chemotherapy with gemcitabine and nab-paclitaxel (gemcitabine/nab-paclitaxel) is recommended for unresectable pancreatic cancer. However, the therapeutic efficacy is attenuated by the antitumor agent-induced activation of nuclear factor-κB (NF-κB). Thalidomide inhibits NF-κB activation,...
Autores principales: | Saito, Nobuhiro, Shirai, Yoshihiro, Uwagawa, Tadashi, Horiuchi, Takashi, Sugano, Hiroshi, Haruki, Koichiro, Shiba, Hiroaki, Ohashi, Toya, Yanaga, Katsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884664/ https://www.ncbi.nlm.nih.gov/pubmed/29644009 http://dx.doi.org/10.18632/oncotarget.24608 |
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