Cargando…

Discovery of PACAP and its receptors in the brain

Pituitary adenylate-cyclase-activating polypeptide (PACAP) is a 27- or 38-amino acid neuropeptide, which belongs to the vasoactive intestinal polypeptide (VIP)/glucagon/secretin family. PACAP shows particularly high homology (~ 68%) to VIP. Because of the high homology of the amino acid sequences of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hirabayashi, Takahiro, Nakamachi, Tomoya, Shioda, Seiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Milan 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884755/ https://www.ncbi.nlm.nih.gov/pubmed/29619773 http://dx.doi.org/10.1186/s10194-018-0855-1

Ejemplares similares

Expression Patterns of PACAP and PAC1R Genes and Anorexigenic Action of PACAP1 and PACAP2 in Zebrafish
por: Nakamachi, Tomoya, et al.
Publicado: (2019)

Unraveling the Specific Ischemic Core and Penumbra Transcriptome in the Permanent Middle Cerebral Artery Occlusion Mouse Model Brain Treated with the Neuropeptide PACAP38
por: Hori, Motohide, et al.
Publicado: (2015)

Transcriptomics and proteomics analyses of the PACAP38 influenced ischemic brain in permanent middle cerebral artery occlusion model mice
por: Hori, Motohide, et al.
Publicado: (2012)

PACAP38 Differentially Effects Genes and CRMP2 Protein Expression in Ischemic Core and Penumbra Regions of Permanent Middle Cerebral Artery Occlusion Model Mice Brain
por: Hori, Motohide, et al.
Publicado: (2014)

Correction: Transcriptomics and proteomics analyses of the PACAP38 influenced ischemic brain in permanent middle cerebral artery occlusion model mice
por: Hori, Motohide, et al.
Publicado: (2013)

Molecular and Physiological Functions of PACAP in Sweat Secretion
por: Yamashita, Michio, et al.
Publicado: (2023)

Two-color Dye-swap DNA Microarray approach toward confident gene expression profiling in PMCAO mouse model for ischemia-related and PACAP38-influenced genes
por: Hori, Motohide, et al.
Publicado: (2015)

PACAP suppresses dry eye signs by stimulating tear secretion
por: Nakamachi, Tomoya, et al.
Publicado: (2016)

Molecular Mechanism for PACAP 38-Induced Neurite Outgrowth in PC12 Cells
por: Shibato, Junko, et al.
Publicado: (2021)

Human mesenchymal stem/stromal cells suppress spinal inflammation in mice with contribution of pituitary adenylate cyclase-activating polypeptide (PACAP)
por: Tsumuraya, Tomomi, et al.
Publicado: (2015)

Pituitary adenylate cyclase-activating polypeptide (PACAP) contributes to the proliferation of hematopoietic progenitor cells in murine bone marrow via PACAP-specific receptor
por: Xu, Zhifang, et al.
Publicado: (2016)

Distribution and protective function of pituitary adenylate cyclase-activating polypeptide in the retina
por: Nakamachi, Tomoya, et al.
Publicado: (2012)

PACAP and its receptors in cranial arteries and mast cells
por: Jansen-Olesen, Inger, et al.
Publicado: (2018)

Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors
por: Lu, Jessica, et al.
Publicado: (2022)

Comprehensive Analysis of Neonatal versus Adult Unilateral Decortication in a Mouse Model Using Behavioral, Neuroanatomical, and DNA Microarray Approaches
por: Yoshikawa, Akira, et al.
Publicado: (2014)

Signal Transduction by VIP and PACAP Receptors
por: Langer, Ingrid, et al.
Publicado: (2022)

PACAP and its role in primary headaches
por: Edvinsson, Lars, et al.
Publicado: (2018)

The PACAP/PAC1 Receptor System and Feeding
por: Sureshkumar, Keerthana, et al.
Publicado: (2021)

Minus Charge Stimulation Prevents LPS-Induced Liver Injury by Reduction of Nitric Oxide
por: Senga, Fujitoshi, et al.
Publicado: (2008)

Unraveling the ischemic brain transcriptome in a permanent middle cerebral artery occlusion mouse model by DNA microarray analysis
por: Hori, Motohide, et al.
Publicado: (2012)

Gp91(phox )(NOX2) in classically activated microglia exacerbates traumatic brain injury
por: Dohi, Kenji, et al.
Publicado: (2010)

Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40
por: Karki, Prasanna, et al.
Publicado: (2015)

The Neuroprotective and Biomarker Potential of PACAP in Human Traumatic Brain Injury
por: Toth, Denes, et al.
Publicado: (2020)

The Potential of the Nose-to-Brain Delivery of PACAP for the Treatment of Neuronal Disease
por: Cherait, Asma, et al.
Publicado: (2023)

PACAP and VIP Neuropeptides’ and Receptors’ Effects on Appetite, Satiety and Metabolism
por: Vu, John P., et al.
Publicado: (2023)

Potential Therapeutic Role of Pituitary Adenylate Cyclase-Activating Polypeptide for Dry Eye Disease
por: Hirabayashi, Takahiro, et al.
Publicado: (2022)

Multimodal Role of PACAP in Glioblastoma
por: D’Amico, Agata Grazia, et al.
Publicado: (2021)

Protective effects of PACAP in ischemia
por: Reglodi, Dora, et al.
Publicado: (2018)

Distribution of PACAP and PAC1 Receptor in the Human Eye
por: Patko, Evelin, et al.
Publicado: (2022)

PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma
por: Waschek, James A., et al.
Publicado: (2018)

PACAP38 and PAC(1) receptor blockade: a new target for headache?
por: Rubio-Beltrán, Eloisa, et al.
Publicado: (2018)

Targeting VIP and PACAP receptor signalling: new therapeutic strategies in multiple sclerosis
por: Tan, Yossan-Var, et al.
Publicado: (2011)

Drug Repositioning For Allosteric Modulation of VIP and PACAP Receptors
por: Langer, Ingrid, et al.
Publicado: (2021)

Effect of PACAP in Central and Peripheral Nerve Injuries
por: Tamas, Andrea, et al.
Publicado: (2012)

Nucleoprotein Diet Ameliorates Arthritis Symptoms in Mice Transgenic for Human T-Cell Leukemia Virus Type I (HTLV-1)
por: Ohtaki, Hirokazu, et al.
Publicado: (2010)

PACAP38 in human models of primary headaches
por: Ashina, Håkan, et al.
Publicado: (2017)

PACAP-38 and PACAP(6–38) Degranulate Rat Meningeal Mast Cells via the Orphan MrgB(3)-Receptor
por: Pedersen, Sara Hougaard, et al.
Publicado: (2019)

PACAP and PAC1 receptor expression in pancreatic ductal carcinoma
por: Ferencz, Sandor, et al.
Publicado: (2019)

Dynamic changes in CGRP, PACAP, and PACAP receptors in the trigeminovascular system of a novel repetitive electrical stimulation rat model: Relevant to migraine
por: Zhang, Qing, et al.
Publicado: (2019)

OMICS Analyses Unraveling Related Gene and Protein-Driven Molecular Mechanisms Underlying PACAP 38-Induced Neurite Outgrowth in PC12 Cells
por: Shibato, Junko, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_egorch4mrjm0k0fk57h64k69tt