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Therapeutic potential of heterocyclic pyrimidine scaffolds
Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heterocycles compounds has confirmed their immense significance in the pathophysiology of diseas...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884769/ https://www.ncbi.nlm.nih.gov/pubmed/29619583 http://dx.doi.org/10.1186/s13065-018-0406-5 |
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author | Kumar, Sanjiv Narasimhan, Balasubramanian |
author_facet | Kumar, Sanjiv Narasimhan, Balasubramanian |
author_sort | Kumar, Sanjiv |
collection | PubMed |
description | Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heterocycles compounds has confirmed their immense significance in the pathophysiology of diseases. Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. The present review article aims to review the work reported on therapeutic potentials of pyrimidine scaffolds which are valuable for medical applications during new generation. [Image: see text] |
format | Online Article Text |
id | pubmed-5884769 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-58847692018-04-11 Therapeutic potential of heterocyclic pyrimidine scaffolds Kumar, Sanjiv Narasimhan, Balasubramanian Chem Cent J Review Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heterocycles compounds has confirmed their immense significance in the pathophysiology of diseases. Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. The present review article aims to review the work reported on therapeutic potentials of pyrimidine scaffolds which are valuable for medical applications during new generation. [Image: see text] Springer International Publishing 2018-04-04 /pmc/articles/PMC5884769/ /pubmed/29619583 http://dx.doi.org/10.1186/s13065-018-0406-5 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Kumar, Sanjiv Narasimhan, Balasubramanian Therapeutic potential of heterocyclic pyrimidine scaffolds |
title | Therapeutic potential of heterocyclic pyrimidine scaffolds |
title_full | Therapeutic potential of heterocyclic pyrimidine scaffolds |
title_fullStr | Therapeutic potential of heterocyclic pyrimidine scaffolds |
title_full_unstemmed | Therapeutic potential of heterocyclic pyrimidine scaffolds |
title_short | Therapeutic potential of heterocyclic pyrimidine scaffolds |
title_sort | therapeutic potential of heterocyclic pyrimidine scaffolds |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884769/ https://www.ncbi.nlm.nih.gov/pubmed/29619583 http://dx.doi.org/10.1186/s13065-018-0406-5 |
work_keys_str_mv | AT kumarsanjiv therapeuticpotentialofheterocyclicpyrimidinescaffolds AT narasimhanbalasubramanian therapeuticpotentialofheterocyclicpyrimidinescaffolds |