Cargando…

Therapeutic potential of heterocyclic pyrimidine scaffolds

Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heterocycles compounds has confirmed their immense significance in the pathophysiology of diseas...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Sanjiv, Narasimhan, Balasubramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884769/
https://www.ncbi.nlm.nih.gov/pubmed/29619583
http://dx.doi.org/10.1186/s13065-018-0406-5
_version_ 1783311869558128640
author Kumar, Sanjiv
Narasimhan, Balasubramanian
author_facet Kumar, Sanjiv
Narasimhan, Balasubramanian
author_sort Kumar, Sanjiv
collection PubMed
description Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heterocycles compounds has confirmed their immense significance in the pathophysiology of diseases. Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. The present review article aims to review the work reported on therapeutic potentials of pyrimidine scaffolds which are valuable for medical applications during new generation. [Image: see text]
format Online
Article
Text
id pubmed-5884769
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-58847692018-04-11 Therapeutic potential of heterocyclic pyrimidine scaffolds Kumar, Sanjiv Narasimhan, Balasubramanian Chem Cent J Review Heterocyclic compounds offer a high degree of structural diversity and have proven to be broadly and economically useful as therapeutic agents. Comprehensive research on diverse therapeutic potentials of heterocycles compounds has confirmed their immense significance in the pathophysiology of diseases. Heterocyclic pyrimidine nucleus, which is an essential base component of the genetic material of deoxyribonucleic acid, demonstrated various biological activities. The present review article aims to review the work reported on therapeutic potentials of pyrimidine scaffolds which are valuable for medical applications during new generation. [Image: see text] Springer International Publishing 2018-04-04 /pmc/articles/PMC5884769/ /pubmed/29619583 http://dx.doi.org/10.1186/s13065-018-0406-5 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Kumar, Sanjiv
Narasimhan, Balasubramanian
Therapeutic potential of heterocyclic pyrimidine scaffolds
title Therapeutic potential of heterocyclic pyrimidine scaffolds
title_full Therapeutic potential of heterocyclic pyrimidine scaffolds
title_fullStr Therapeutic potential of heterocyclic pyrimidine scaffolds
title_full_unstemmed Therapeutic potential of heterocyclic pyrimidine scaffolds
title_short Therapeutic potential of heterocyclic pyrimidine scaffolds
title_sort therapeutic potential of heterocyclic pyrimidine scaffolds
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884769/
https://www.ncbi.nlm.nih.gov/pubmed/29619583
http://dx.doi.org/10.1186/s13065-018-0406-5
work_keys_str_mv AT kumarsanjiv therapeuticpotentialofheterocyclicpyrimidinescaffolds
AT narasimhanbalasubramanian therapeuticpotentialofheterocyclicpyrimidinescaffolds