Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy

This study is to analyze the radiation dose of head, body and tail of hippocampus (HC) of nasopharyngeal carcinoma (NPC) patients treated with intensity modulated radiotherapy (IMRT). Evaluate cognitive function of patients with Wechsler adult intelligence scale-Chinese revised (WAIS-CR). HC were se...

Descripción completa

Detalles Bibliográficos
Autores principales: Zong-wen, Sun, lei, Shi, Qinglin, Li, yue, Kong, feng-lei, Du, Tie-ming, Xie, Yong-hong, Hua, Qiao-ying, Hu, Xiao-zhong, Chen, Yuan-yuan, Chen, Ming, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884782/
https://www.ncbi.nlm.nih.gov/pubmed/29618828
http://dx.doi.org/10.1038/s41598-018-23127-6
_version_ 1783311872576978944
author Zong-wen, Sun
lei, Shi
Qinglin, Li
yue, Kong
feng-lei, Du
Tie-ming, Xie
Yong-hong, Hua
Qiao-ying, Hu
Xiao-zhong, Chen
Yuan-yuan, Chen
Ming, Chen
author_facet Zong-wen, Sun
lei, Shi
Qinglin, Li
yue, Kong
feng-lei, Du
Tie-ming, Xie
Yong-hong, Hua
Qiao-ying, Hu
Xiao-zhong, Chen
Yuan-yuan, Chen
Ming, Chen
author_sort Zong-wen, Sun
collection PubMed
description This study is to analyze the radiation dose of head, body and tail of hippocampus (HC) of nasopharyngeal carcinoma (NPC) patients treated with intensity modulated radiotherapy (IMRT). Evaluate cognitive function of patients with Wechsler adult intelligence scale-Chinese revised (WAIS-CR). HC were segmented into HC head (HH), HC body (HB) and HC tail (HT) and the indexes were then analyzed. WAIS-CR was tested before and 3months after radiotherapy. The mean radiation dose of left and right HC was (1147 ± 976)cGy, (1011 ± 602)cGy respectively. The radiation dose and the volume exposed in different dose of HH, HB and HT decreased in turn. For 5 patients, before and after radiotherapy, the regular-order score was 8.60 ± 1.34, 8.0 ± 1.00 (P = 0.43), while the reverse-order score was 5.80 ± 0.84, 5.20 ± 0.84 (P = 0.07). The radiation dose of HH, HB and HT was different, and the radiation dose of HH was the highest, which should be emphasized especially.
format Online
Article
Text
id pubmed-5884782
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-58847822018-04-09 Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy Zong-wen, Sun lei, Shi Qinglin, Li yue, Kong feng-lei, Du Tie-ming, Xie Yong-hong, Hua Qiao-ying, Hu Xiao-zhong, Chen Yuan-yuan, Chen Ming, Chen Sci Rep Article This study is to analyze the radiation dose of head, body and tail of hippocampus (HC) of nasopharyngeal carcinoma (NPC) patients treated with intensity modulated radiotherapy (IMRT). Evaluate cognitive function of patients with Wechsler adult intelligence scale-Chinese revised (WAIS-CR). HC were segmented into HC head (HH), HC body (HB) and HC tail (HT) and the indexes were then analyzed. WAIS-CR was tested before and 3months after radiotherapy. The mean radiation dose of left and right HC was (1147 ± 976)cGy, (1011 ± 602)cGy respectively. The radiation dose and the volume exposed in different dose of HH, HB and HT decreased in turn. For 5 patients, before and after radiotherapy, the regular-order score was 8.60 ± 1.34, 8.0 ± 1.00 (P = 0.43), while the reverse-order score was 5.80 ± 0.84, 5.20 ± 0.84 (P = 0.07). The radiation dose of HH, HB and HT was different, and the radiation dose of HH was the highest, which should be emphasized especially. Nature Publishing Group UK 2018-04-04 /pmc/articles/PMC5884782/ /pubmed/29618828 http://dx.doi.org/10.1038/s41598-018-23127-6 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Zong-wen, Sun
lei, Shi
Qinglin, Li
yue, Kong
feng-lei, Du
Tie-ming, Xie
Yong-hong, Hua
Qiao-ying, Hu
Xiao-zhong, Chen
Yuan-yuan, Chen
Ming, Chen
Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
title Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
title_full Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
title_fullStr Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
title_full_unstemmed Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
title_short Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
title_sort results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884782/
https://www.ncbi.nlm.nih.gov/pubmed/29618828
http://dx.doi.org/10.1038/s41598-018-23127-6
work_keys_str_mv AT zongwensun resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT leishi resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT qinglinli resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT yuekong resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT fengleidu resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT tiemingxie resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT yonghonghua resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT qiaoyinghu resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT xiaozhongchen resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT yuanyuanchen resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy
AT mingchen resultsoftheradiationdoseofheadbodyandtailofhippocampusinnasopharyngealcarcinomapatientstreatedwithintensitymodulatedradiotherapy

Ejemplares similares