SMAD6 overexpression leads to accelerated myogenic differentiation of LMNA mutated cells

LMNA gene encodes lamins A and C, two major components of the nuclear lamina, a network of intermediate filaments underlying the inner nuclear membrane. Most of LMNA mutations are associated with cardiac and/or skeletal muscles defects. Muscle laminopathies include Emery-Dreifuss Muscular Dystrophy,...

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Detalles Bibliográficos
Autores principales: Janin, Alexandre, Bauer, Delphine, Ratti, Francesca, Valla, Camille, Bertrand, Anne, Christin, Emilie, Chopin, Emilie, Streichenberger, Nathalie, Bonne, Gisèle, Gache, Vincent, Cohen, Tatiana, Méjat, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884786/
https://www.ncbi.nlm.nih.gov/pubmed/29618840
http://dx.doi.org/10.1038/s41598-018-23918-x

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