Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus

The persistent public health threat of infection with Middle East respiratory syndrome coronavirus (MERS-CoV) highlights the need for an effective and safe MERS-CoV vaccine. In this study, we prepared and vaccinated mice with either a Spike (S) protein or inactivated whole MERS-CoV (IV) with a combi...

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Detalles Bibliográficos
Autores principales: Deng, Yao, Lan, Jiaming, Bao, Linlin, Huang, Baoying, Ye, Fei, Chen, Yingzhu, Yao, Yanfeng, Wang, Wenling, Qin, Chuan, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884803/
https://www.ncbi.nlm.nih.gov/pubmed/29618723
http://dx.doi.org/10.1038/s41426-018-0056-7

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