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The genetic diversity within the 1.4 kb HLA-G 5′ upstream regulatory region moderately impacts on cellular microenvironment responses
The HLA-G 5’URR extending 1.4 kb from the ATG presents a unique set of regulatory elements among HLA genes. Several variable sites have been described that coincide with or are close to these elements, thus HLA-G 5′URR polymorphism might influence the HLA-G expression level. We cloned the ten most f...
Autores principales: | Dias, Fabrício C., Bertol, Bruna C., Poras, Isabelle, Souto, Bruno M., Mendes-Junior, Celso T., Castelli, Erick C., Gineau, Laure, Sabbagh, Audrey, Rouas-Freiss, Nathalie, Carosella, Edgardo D., Donadi, Eduardo A., Moreau, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884815/ https://www.ncbi.nlm.nih.gov/pubmed/29618829 http://dx.doi.org/10.1038/s41598-018-24009-7 |
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