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The genetic diversity within the 1.4 kb HLA-G 5′ upstream regulatory region moderately impacts on cellular microenvironment responses

The HLA-G 5’URR extending 1.4 kb from the ATG presents a unique set of regulatory elements among HLA genes. Several variable sites have been described that coincide with or are close to these elements, thus HLA-G 5′URR polymorphism might influence the HLA-G expression level. We cloned the ten most f...

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Detalles Bibliográficos
Autores principales: Dias, Fabrício C., Bertol, Bruna C., Poras, Isabelle, Souto, Bruno M., Mendes-Junior, Celso T., Castelli, Erick C., Gineau, Laure, Sabbagh, Audrey, Rouas-Freiss, Nathalie, Carosella, Edgardo D., Donadi, Eduardo A., Moreau, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884815/
https://www.ncbi.nlm.nih.gov/pubmed/29618829
http://dx.doi.org/10.1038/s41598-018-24009-7

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