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Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year
Japan’s governmental recommendation of HPV vaccine has now been suspended for more than 4 years. In and before 2013, the targets of 20-year-old cervical cancer screening were females born in and before 1993, i.e., those who could not have received HPV vaccination because it was not yet publicly intr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884824/ https://www.ncbi.nlm.nih.gov/pubmed/29618795 http://dx.doi.org/10.1038/s41598-018-23947-6 |
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author | Ueda, Yutaka Yagi, Asami Nakayama, Tomio Hirai, Kei Ikeda, Sayaka Sekine, Masayuki Miyagi, Etsuko Enomoto, Takayuki |
author_facet | Ueda, Yutaka Yagi, Asami Nakayama, Tomio Hirai, Kei Ikeda, Sayaka Sekine, Masayuki Miyagi, Etsuko Enomoto, Takayuki |
author_sort | Ueda, Yutaka |
collection | PubMed |
description | Japan’s governmental recommendation of HPV vaccine has now been suspended for more than 4 years. In and before 2013, the targets of 20-year-old cervical cancer screening were females born in and before 1993, i.e., those who could not have received HPV vaccination because it was not yet publicly introduced. The targets during 2014–2019 are, or will be, those born in 1994–1999, i.e., those who came of age during a period with the highest HPV immunization rate. We analyzed the statistical data for each birth year, for the cumulative HPV vaccination rates achieved as of age 16, and for the corresponding results of cervical cancer screening at age 20. The rate of abnormal findings in cervical cytology increased slightly from 3.68% in 2010 (birth year: 1990) to 4.35% in 2013 (birth year: 1993); however, it dynamically dropped to 2.99% in 2014 (birth year: 1994) and 3.03% in 2015 (birth year: 1995). In total, the rate of abnormal findings in cervical cytology was 3.96% in 2010–2013, but significantly dropped to 3.01% in 2014–2015 (p = 0.014). This is the first description of dynamic changes occurring in the abnormal rate of cervical cancer screening as a result of positive changes in national HPV vaccination rates. |
format | Online Article Text |
id | pubmed-5884824 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-58848242018-04-09 Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year Ueda, Yutaka Yagi, Asami Nakayama, Tomio Hirai, Kei Ikeda, Sayaka Sekine, Masayuki Miyagi, Etsuko Enomoto, Takayuki Sci Rep Article Japan’s governmental recommendation of HPV vaccine has now been suspended for more than 4 years. In and before 2013, the targets of 20-year-old cervical cancer screening were females born in and before 1993, i.e., those who could not have received HPV vaccination because it was not yet publicly introduced. The targets during 2014–2019 are, or will be, those born in 1994–1999, i.e., those who came of age during a period with the highest HPV immunization rate. We analyzed the statistical data for each birth year, for the cumulative HPV vaccination rates achieved as of age 16, and for the corresponding results of cervical cancer screening at age 20. The rate of abnormal findings in cervical cytology increased slightly from 3.68% in 2010 (birth year: 1990) to 4.35% in 2013 (birth year: 1993); however, it dynamically dropped to 2.99% in 2014 (birth year: 1994) and 3.03% in 2015 (birth year: 1995). In total, the rate of abnormal findings in cervical cytology was 3.96% in 2010–2013, but significantly dropped to 3.01% in 2014–2015 (p = 0.014). This is the first description of dynamic changes occurring in the abnormal rate of cervical cancer screening as a result of positive changes in national HPV vaccination rates. Nature Publishing Group UK 2018-04-04 /pmc/articles/PMC5884824/ /pubmed/29618795 http://dx.doi.org/10.1038/s41598-018-23947-6 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Ueda, Yutaka Yagi, Asami Nakayama, Tomio Hirai, Kei Ikeda, Sayaka Sekine, Masayuki Miyagi, Etsuko Enomoto, Takayuki Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year |
title | Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year |
title_full | Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year |
title_fullStr | Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year |
title_full_unstemmed | Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year |
title_short | Dynamic changes in Japan’s prevalence of abnormal findings in cervical cytology depending on birth year |
title_sort | dynamic changes in japan’s prevalence of abnormal findings in cervical cytology depending on birth year |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884824/ https://www.ncbi.nlm.nih.gov/pubmed/29618795 http://dx.doi.org/10.1038/s41598-018-23947-6 |
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