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Altered DNA repair; an early pathogenic pathway in Alzheimer’s disease and obesity

Unrepaired DNA double-strand breaks (DSBs) are lethal. The present study compared the extent of DSBs, neuronal apoptosis, and status of two major DSB repair pathways - homologous combinational repair (HR) and nonhomologous end-joining (NHEJ) - in hippocampus of 5–6 month and 16–18 month-old wild-typ...

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Detalles Bibliográficos
Autores principales:	Yu, Hao, Harrison, Fiona Edith, Xia, Fen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884847/ https://www.ncbi.nlm.nih.gov/pubmed/29618789 http://dx.doi.org/10.1038/s41598-018-23644-4

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