Cargando…

Multifactorial chromosomal variants regulate polymyxin resistance in extensively drug-resistant Klebsiella pneumoniae

Extensively drug-resistant Klebsiella pneumoniae (XDR-KP) infections cause high mortality and are disseminating globally. Identifying the genetic basis underpinning resistance allows for rapid diagnosis and treatment. XDR isolates sourced from Greece and Brazil, including 19 polymyxin-resistant and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pitt, Miranda E., Elliott, Alysha G., Cao, Minh Duc, Ganesamoorthy, Devika, Karaiskos, Ilias, Giamarellou, Helen, Abboud, Cely S., Blaskovich, Mark A. T., Cooper, Matthew A., Coin, Lachlan J. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885010/ https://www.ncbi.nlm.nih.gov/pubmed/29431605 http://dx.doi.org/10.1099/mgen.0.000158

Ejemplares similares

Complete Genome Sequence of Klebsiella quasipneumoniae subsp. similipneumoniae Strain ATCC 700603
por: Elliott, Alysha G., et al.
Publicado: (2016)

Streaming algorithms for identification of pathogens and antibiotic resistance potential from real-time MinION(TM) sequencing
por: Cao, Minh Duc, et al.
Publicado: (2016)

Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches
por: Karaiskos, Ilias, et al.
Publicado: (2014)

Scaffolding and completing genome assemblies in real-time with nanopore sequencing
por: Cao, Minh Duc, et al.
Publicado: (2017)

Evaluating the genome and resistome of extensively drug-resistant Klebsiella pneumoniae using native DNA and RNA Nanopore sequencing
por: Pitt, Miranda E, et al.
Publicado: (2020)

Nationwide epidemiology of carbapenem resistant Klebsiella pneumoniae isolates from Greek hospitals, with regards to plazomicin and aminoglycoside resistance
por: Galani, Irene, et al.
Publicado: (2019)

GtTR: Bayesian estimation of absolute tandem repeat copy number using sequence capture and high throughput sequencing
por: Ganesamoorthy, Devika, et al.
Publicado: (2018)

Simulating the dynamics of targeted capture sequencing with CapSim
por: Cao, Minh Duc, et al.
Publicado: (2018)

Correction to: Nationwide epidemiology of carbapenem resistant Klebsiella pneumoniae isolates from Greek hospitals, with regards to plazomicin and aminoglycoside resistance
por: Galani, Irene, et al.
Publicado: (2019)

Evaluation of Activity and Emergence of Resistance of Polymyxin B and ZTI-01 (Fosfomycin for Injection) against KPC-Producing Klebsiella pneumoniae
por: Diep, John K., et al.
Publicado: (2018)

Current and Potential Therapeutic Options for Infections Caused by Difficult-to-Treat and Pandrug Resistant Gram-Negative Bacteria in Critically Ill Patients
por: Giamarellou, Helen, et al.
Publicado: (2022)

npInv: accurate detection and genotyping of inversions using long read sub-alignment
por: Shao, Haojing, et al.
Publicado: (2018)

Effect of polymyxin B-containing regimens on renal function for the treatment of carbapenem-resistant Enterobacteriacea mediastinitis()
por: Abboud, Cely Saad, et al.
Publicado: (2017)

Outbreak of KPC-2-producing Klebsiella pneumoniae endowed with ceftazidime-avibactam resistance mediated through a VEB-1-mutant (VEB-25), Greece, September to October 2019
por: Galani, Irene, et al.
Publicado: (2020)

sCNAphase: using haplotype resolved read depth to genotype somatic copy number alterations from low cellularity aneuploid tumors
por: Chen, Wenhan, et al.
Publicado: (2017)

Polymyxin B Resistance in Carbapenem-Resistant Klebsiella pneumoniae, São Paulo, Brazil
por: Bartolleti, Flávia, et al.
Publicado: (2016)

487 Infections Caused by Enterobacteriaceae Species following Cardiac Surgery: Impact of Polymyxin Resistance on Treatment Outcomes
por: Abboud, Cely Saad, et al.
Publicado: (2014)

Structure-Function Studies of Polymyxin B Lipononapeptides
por: Gallardo-Godoy, Alejandra, et al.
Publicado: (2019)

Carbapenem-Sparing Strategies for ESBL Producers: When and How
por: Karaiskos, Ilias, et al.
Publicado: (2020)

Resveratrol enhances the antimicrobial effect of polymyxin B on Klebsiella pneumoniae and Escherichia coli isolates with polymyxin B resistance
por: Liu, Li, et al.
Publicado: (2020)

Epidemiology and resistance phenotypes of carbapenemase-producing Klebsiella pneumoniae in Greece, 2014 to 2016
por: Galani, Irene, et al.
Publicado: (2018)

Molecular Analysis of Polymyxin Resistance among Carbapenemase-Producing Klebsiella pneumoniae in Colombia
por: De La Cadena, Elsa, et al.
Publicado: (2021)

Antimicrobial peptides against polymyxin-resistant Klebsiella pneumoniae: a patent review
por: de Souza, Gleyce Hellen de Almeida, et al.
Publicado: (2023)

Difficulty in detecting low levels of polymyxin resistance in clinical Klebsiella pneumoniae isolates: evaluation of Rapid Polymyxin NP test, Colispot Test and SuperPolymyxin medium
por: Conceição-Neto, O.C., et al.
Publicado: (2020)

Nanopore sequencing as a scalable, cost-effective platform for analyzing polyclonal vector integration sites following clinical T cell therapy
por: Zhang, Ping, et al.
Publicado: (2020)

Resistance evolution of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11 during treatment with tigecycline and polymyxin
por: Jin, Xi, et al.
Publicado: (2021)

Metals to combat antimicrobial resistance
por: Frei, Angelo, et al.
Publicado: (2023)

Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B
por: Gallardo-Godoy, Alejandra, et al.
Publicado: (2016)

Whole genome deep sequencing analysis of cell-free DNA in samples with low tumour content
por: Ganesamoorthy, Devika, et al.
Publicado: (2022)

CrrB Positively Regulates High-Level Polymyxin Resistance and Virulence in Klebsiella pneumoniae
por: McConville, Thomas H., et al.
Publicado: (2020)

Combined effect of Polymyxin B and Tigecycline to overcome Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae
por: Tian, Yuan, et al.
Publicado: (2021)

Review and analysis of the overlapping threats of carbapenem and polymyxin resistant E. coli and Klebsiella in Africa
por: Venne, Danielle M., et al.
Publicado: (2023)

Ongoing human chromosome end extension revealed by analysis of BioNano and nanopore data
por: Shao, Haojing, et al.
Publicado: (2018)

Non-clonal occurrence of pmrB mutations associated with polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae in Brazil
por: Rodrigues, Ana Claudia Souza, et al.
Publicado: (2019)

Nosocomial Outbreak of Extensively Drug-Resistant (Polymyxin B and Carbapenem) Klebsiella pneumoniae in a Collapsed University Hospital Due to COVID-19 Pandemic
por: Gaspar, Gilberto G., et al.
Publicado: (2022)

Polymyxin B and fusidic acid, a novel potent synergistic combination against Klebsiella pneumoniae and Escherichia coli isolates with polymyxin B resistance
por: Chen, Shuying, et al.
Publicado: (2023)

Predicting Phenotypic Polymyxin Resistance in Klebsiella pneumoniae through Machine Learning Analysis of Genomic Data
por: Macesic, Nenad, et al.
Publicado: (2020)

Genetic Diversity of Virulent Polymyxin-Resistant Klebsiella aerogenes Isolated from Intensive Care Units
por: da Silva, Kesia Esther, et al.
Publicado: (2022)

Early use of polymyxin B reduces the mortality of carbapenem-resistant Klebsiella pneumoniae bloodstream infection
por: Liang, Qiqiang, et al.
Publicado: (2019)

Pharmacokinetics/pharmacodynamics of polymyxin B in patients with bloodstream infection caused by carbapenem-resistant Klebsiella pneumoniae
por: Yu, Zhenwei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vbtpgaicj5c5p1m75da7mnkpes