Cargando…

Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola

OBJECTIVE: Pulmonary embolism (PE) is a potentially fatal disease. In Angola, few data are available on its occurrence. The aim of the study was to characterise the clinical profile, management and outcomes of patients with PE. METHODS: A retrospective observational study was conducted at the Girass...

Descripción completa

Detalles Bibliográficos
Autores principales: Manuel, Ana, Peralta, Tomáz, Salas, Abel, Ricardo, José, Sabola, Pedro, Baião, Domingas, Martins, Telmo, Júnior, António Pedro Filipe, Aufico, Adelina, Africano, Rui, Silva, Adelaide, Sotolongo, Carlos, Neto, António Dias, Sabino, Vasco, van Dúnem, Joaquim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885046/
https://www.ncbi.nlm.nih.gov/pubmed/28556850
http://dx.doi.org/10.5830/CVJA-2017-017
_version_ 1783311922470322176
author Manuel, Ana
Peralta, Tomáz
Salas, Abel
Ricardo, José
Sabola, Pedro
Baião, Domingas
Martins, Telmo
Júnior, António Pedro Filipe
Aufico, Adelina
Africano, Rui
Silva, Adelaide
Sotolongo, Carlos
Sotolongo, Carlos
Neto, António Dias
Sabino, Vasco
van Dúnem, Joaquim
author_facet Manuel, Ana
Peralta, Tomáz
Salas, Abel
Ricardo, José
Sabola, Pedro
Baião, Domingas
Martins, Telmo
Júnior, António Pedro Filipe
Aufico, Adelina
Africano, Rui
Silva, Adelaide
Sotolongo, Carlos
Sotolongo, Carlos
Neto, António Dias
Sabino, Vasco
van Dúnem, Joaquim
author_sort Manuel, Ana
collection PubMed
description OBJECTIVE: Pulmonary embolism (PE) is a potentially fatal disease. In Angola, few data are available on its occurrence. The aim of the study was to characterise the clinical profile, management and outcomes of patients with PE. METHODS: A retrospective observational study was conducted at the Girassol Clinic in Luanda, Angola. The medical records of patients admitted to the intensive care unit were analysed from 2011 to 2015. RESULTS: Fifty patients were included and the median age was 50.5 ± 17.8 years. Dyspnoea and immobilisation for more than 72 hours were the most frequently seen risk factors at admission; 28% of the patients had massive PE, 36% sub-massive PE, 28% were haemodynamically unstable at admission and 30% had a very high risk of mortality. The in-hospital mortality rate was 20%. CONCLUSIONS: The clinical characteristics of our patients were similar to those described in the literature. The high prevalence of patients with very high risk at admisson highlights the need to investigate the cause of worst cardiovascular disease outcomes in Africans.
format Online
Article
Text
id pubmed-5885046
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Clinics Cardive Publishing
record_format MEDLINE/PubMed
spelling pubmed-58850462018-04-13 Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola Manuel, Ana Peralta, Tomáz Salas, Abel Ricardo, José Sabola, Pedro Baião, Domingas Martins, Telmo Júnior, António Pedro Filipe Aufico, Adelina Africano, Rui Silva, Adelaide Sotolongo, Carlos Sotolongo, Carlos Neto, António Dias Sabino, Vasco van Dúnem, Joaquim Cardiovasc J Afr Cardiovascular Topics OBJECTIVE: Pulmonary embolism (PE) is a potentially fatal disease. In Angola, few data are available on its occurrence. The aim of the study was to characterise the clinical profile, management and outcomes of patients with PE. METHODS: A retrospective observational study was conducted at the Girassol Clinic in Luanda, Angola. The medical records of patients admitted to the intensive care unit were analysed from 2011 to 2015. RESULTS: Fifty patients were included and the median age was 50.5 ± 17.8 years. Dyspnoea and immobilisation for more than 72 hours were the most frequently seen risk factors at admission; 28% of the patients had massive PE, 36% sub-massive PE, 28% were haemodynamically unstable at admission and 30% had a very high risk of mortality. The in-hospital mortality rate was 20%. CONCLUSIONS: The clinical characteristics of our patients were similar to those described in the literature. The high prevalence of patients with very high risk at admisson highlights the need to investigate the cause of worst cardiovascular disease outcomes in Africans. Clinics Cardive Publishing 2017 /pmc/articles/PMC5885046/ /pubmed/28556850 http://dx.doi.org/10.5830/CVJA-2017-017 Text en Copyright © 2015 Clinics Cardive Publishing http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Cardiovascular Topics
Manuel, Ana
Peralta, Tomáz
Salas, Abel
Ricardo, José
Sabola, Pedro
Baião, Domingas
Martins, Telmo
Júnior, António Pedro Filipe
Aufico, Adelina
Africano, Rui
Silva, Adelaide
Sotolongo, Carlos
Sotolongo, Carlos
Neto, António Dias
Sabino, Vasco
van Dúnem, Joaquim
Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola
title Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola
title_full Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola
title_fullStr Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola
title_full_unstemmed Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola
title_short Clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in Angola
title_sort clinical profile, management and outcomes of patients with pulmonary embolism: a retrospective tertiary centre study in angola
topic Cardiovascular Topics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885046/
https://www.ncbi.nlm.nih.gov/pubmed/28556850
http://dx.doi.org/10.5830/CVJA-2017-017
work_keys_str_mv AT manuelana clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT peraltatomaz clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT salasabel clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT ricardojose clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT sabolapedro clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT baiaodomingas clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT martinstelmo clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT juniorantoniopedrofilipe clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT auficoadelina clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT africanorui clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT silvaadelaide clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT sotolongocarlos clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT sotolongocarlos clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT netoantoniodias clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT sabinovasco clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola
AT vandunemjoaquim clinicalprofilemanagementandoutcomesofpatientswithpulmonaryembolismaretrospectivetertiarycentrestudyinangola