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The role of hypoxia in shaping the recruitment of proangiogenic and immunosuppressive cells in the tumor microenvironment

Hypoxia characterizes growing tumors and contributes significantly to their aggressiveness. Hypoxia-inducible factors (HIFs 1 and 2) are stabilized and act differentially as transcription factors on tumor growth and are responsible for important cancer hallmarks such as pathologic angiogenesis, cell...

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Detalles Bibliográficos
Autores principales: Chouaib, Salem, Umansky, Viktor, Kieda, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885081/
https://www.ncbi.nlm.nih.gov/pubmed/29628788
http://dx.doi.org/10.5114/wo.2018.73874