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Heme oxygenase inhibition in cancers: possible tools and targets

Heme oxygenase-1 (HO-1, encoded by HMOX1) through degradation of pro-oxidant heme into carbon monoxide (CO), ferrous ions (Fe(2+)) and biliverdin, exhibits cytoprotective, anti-apoptotic and anti-inflammatory properties. All of these potentially beneficial functions of HO-1 may play an important rol...

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Detalles Bibliográficos
Autores principales: Podkalicka, Paulina, Mucha, Olga, Józkowicz, Alicja, Dulak, Józef, Łoboda, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885082/
https://www.ncbi.nlm.nih.gov/pubmed/29628790
http://dx.doi.org/10.5114/wo.2018.73879