Cargando…

Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina

OBJECTIVE: To describe the incidence of and risk factors for delirium in the intensive care unit of a tertiary care teaching hospital in Argentina and to conduct the first non-European study exploring the performance of the PREdiction of DELIRium in ICu patients (PRE-DELIRIC) model. METHODS: Prospec...

Descripción completa

Detalles Bibliográficos
Autores principales: Sosa, Fernando Ariel, Roberti, Javier, Franco, Margarita Tovar, Kleinert, María Mercedes, Patrón, Agustina Risso, Osatnik, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Medicina Intensiva Brasileira - AMIB 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885231/
https://www.ncbi.nlm.nih.gov/pubmed/29742219
http://dx.doi.org/10.5935/0103-507X.20180010
_version_ 1783311947936038912
author Sosa, Fernando Ariel
Roberti, Javier
Franco, Margarita Tovar
Kleinert, María Mercedes
Patrón, Agustina Risso
Osatnik, Javier
author_facet Sosa, Fernando Ariel
Roberti, Javier
Franco, Margarita Tovar
Kleinert, María Mercedes
Patrón, Agustina Risso
Osatnik, Javier
author_sort Sosa, Fernando Ariel
collection PubMed
description OBJECTIVE: To describe the incidence of and risk factors for delirium in the intensive care unit of a tertiary care teaching hospital in Argentina and to conduct the first non-European study exploring the performance of the PREdiction of DELIRium in ICu patients (PRE-DELIRIC) model. METHODS: Prospective observational study in a 20-bed intensive care unit of a tertiary care teaching hospital in Buenos Aires, Argentina. The PRE-DELIRIC model was applied to 178 consecutive patients within 24 hours of admission to the intensive care unit; delirium was assessed with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). RESULTS: The mean age was 64.3 ± 17.9 years. The median time of stay in the intensive care unit was 6 (range, 2 - 56) days. Of the total number of patients, 49/178 (27.5%) developed delirium, defined as a positive CAM-ICU assessment, during their stay in the intensive care unit. Patients in the delirium group were significantly older and had a significantly higher Acute Physiological and Chronic Health Evaluation II (APACHE II) score. The mortality rate in the intensive care unit was 14.6%; no significant difference was observed between the two groups. Predictive factors for the development of delirium were increased age, prolonged intensive care unit stay, and opioid use. The area under the curve for the PRE-DELIRIC model was 0.83 (95%CI; 0.77 - 0.90). CONCLUSIONS: The observed incidence of delirium highlights the importance of this problem in the intensive care unit setting. In this first study conducted outside Europe, PRE-DELIRIC accurately predicted the development of delirium.
format Online
Article
Text
id pubmed-5885231
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Associação de Medicina Intensiva Brasileira - AMIB
record_format MEDLINE/PubMed
spelling pubmed-58852312018-04-09 Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina Sosa, Fernando Ariel Roberti, Javier Franco, Margarita Tovar Kleinert, María Mercedes Patrón, Agustina Risso Osatnik, Javier Rev Bras Ter Intensiva Original Articles OBJECTIVE: To describe the incidence of and risk factors for delirium in the intensive care unit of a tertiary care teaching hospital in Argentina and to conduct the first non-European study exploring the performance of the PREdiction of DELIRium in ICu patients (PRE-DELIRIC) model. METHODS: Prospective observational study in a 20-bed intensive care unit of a tertiary care teaching hospital in Buenos Aires, Argentina. The PRE-DELIRIC model was applied to 178 consecutive patients within 24 hours of admission to the intensive care unit; delirium was assessed with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). RESULTS: The mean age was 64.3 ± 17.9 years. The median time of stay in the intensive care unit was 6 (range, 2 - 56) days. Of the total number of patients, 49/178 (27.5%) developed delirium, defined as a positive CAM-ICU assessment, during their stay in the intensive care unit. Patients in the delirium group were significantly older and had a significantly higher Acute Physiological and Chronic Health Evaluation II (APACHE II) score. The mortality rate in the intensive care unit was 14.6%; no significant difference was observed between the two groups. Predictive factors for the development of delirium were increased age, prolonged intensive care unit stay, and opioid use. The area under the curve for the PRE-DELIRIC model was 0.83 (95%CI; 0.77 - 0.90). CONCLUSIONS: The observed incidence of delirium highlights the importance of this problem in the intensive care unit setting. In this first study conducted outside Europe, PRE-DELIRIC accurately predicted the development of delirium. Associação de Medicina Intensiva Brasileira - AMIB 2018 /pmc/articles/PMC5885231/ /pubmed/29742219 http://dx.doi.org/10.5935/0103-507X.20180010 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Sosa, Fernando Ariel
Roberti, Javier
Franco, Margarita Tovar
Kleinert, María Mercedes
Patrón, Agustina Risso
Osatnik, Javier
Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina
title Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina
title_full Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina
title_fullStr Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina
title_full_unstemmed Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina
title_short Assessment of delirium using the PRE-DELIRIC model in an intensive care unit in Argentina
title_sort assessment of delirium using the pre-deliric model in an intensive care unit in argentina
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885231/
https://www.ncbi.nlm.nih.gov/pubmed/29742219
http://dx.doi.org/10.5935/0103-507X.20180010
work_keys_str_mv AT sosafernandoariel assessmentofdeliriumusingthepredeliricmodelinanintensivecareunitinargentina
AT robertijavier assessmentofdeliriumusingthepredeliricmodelinanintensivecareunitinargentina
AT francomargaritatovar assessmentofdeliriumusingthepredeliricmodelinanintensivecareunitinargentina
AT kleinertmariamercedes assessmentofdeliriumusingthepredeliricmodelinanintensivecareunitinargentina
AT patronagustinarisso assessmentofdeliriumusingthepredeliricmodelinanintensivecareunitinargentina
AT osatnikjavier assessmentofdeliriumusingthepredeliricmodelinanintensivecareunitinargentina