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KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2
BACKGROUND: Kidney cancer and clear cell renal carcinoma (ccRCC) are the 16th most common cause of death worldwide. ccRCC is often metastasized at diagnosis, and surgery remains the main treatment; therefore, early diagnosis and new therapeutic strategies are highly desirable. KAT inhibitor CPTH2 lo...
Autores principales: | Cocco, Elisa, Leo, Manuela, Canzonetta, Claudia, Di Vito, Serena, Mai, Antonello, Rotili, Dante, Di Napoli, Arianna, Vecchione, Andrea, De Nunzio, Cosimo, Filetici, Patrizia, Stoppacciaro, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885315/ https://www.ncbi.nlm.nih.gov/pubmed/29632619 http://dx.doi.org/10.1186/s13148-018-0473-4 |
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