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A simulation study investigating power estimates in phenome-wide association studies

BACKGROUND: Phenome-wide association studies (PheWAS) are a high-throughput approach to evaluate comprehensive associations between genetic variants and a wide range of phenotypic measures. PheWAS has varying sample sizes for quantitative traits, and variable numbers of cases and controls for binary...

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Detalles Bibliográficos
Autores principales:	Verma, Anurag, Bradford, Yuki, Dudek, Scott, Lucas, Anastasia M., Verma, Shefali S., Pendergrass, Sarah A., Ritchie, Marylyn D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885318/ https://www.ncbi.nlm.nih.gov/pubmed/29618318 http://dx.doi.org/10.1186/s12859-018-2135-0

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