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Genetic analysis of Wnt/PCP genes in neural tube defects

BACKGROUND: Mouse homozygous mutants in Wnt/planar cell polarity (PCP) pathway genes have been shown to cause neural tube defects (NTDs) through the disruption of normal morphogenetic processes critical to neural tube closure (NTC). Knockout mice that are heterozygotes of single PCP genes likely fai...

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Detalles Bibliográficos
Autores principales:	Chen, Zhongzhong, Lei, Yunping, Cao, Xuanye, Zheng, Yufang, Wang, Fang, Bao, Yihua, Peng, Rui, Finnell, Richard H., Zhang, Ting, Wang, Hongyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885375/ https://www.ncbi.nlm.nih.gov/pubmed/29618362 http://dx.doi.org/10.1186/s12920-018-0355-9

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