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Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation

BACKGROUND: Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. CASE PRESENTATION: A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in Trinid...

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Detalles Bibliográficos
Autores principales: Schwartz, Kevin L., Chan, Tiffany, Rai, Nanky, Murphy, Kellie E., Whittle, Wendy, Drebot, Michael A., Gubbay, Jonathan, Boggild, Andrea K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885377/
https://www.ncbi.nlm.nih.gov/pubmed/29632700
http://dx.doi.org/10.1186/s40794-018-0062-8
Descripción
Sumario:BACKGROUND: Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. CASE PRESENTATION: A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in Trinidad presented with one-month of fever, headache, and myalgia with persistent viremia. Significant fetal abnormalities were identified at 14-week ultrasound, which is the earliest ultrasound to describe a severely affected fetus following Zika virus infection to our knowledge. CONCLUSIONS: We discuss the implications of prolonged maternal viremia and the spectrum of congenital Zika syndrome detectable by fetal ultrasound.