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Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling

OBJECTIVE: Increased monocytes, particularly the inflammatory subset, are associated with accelerated atherosclerosis in diabetes through thus far incompletely defined mechanisms. The present study tested the hypothesis that advanced glycation end products (AGEs) promote bone marrow monocytes to pro...

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Detalles Bibliográficos
Autores principales: Jin, Xian, Liu, Liang, Zhang, Yaping, Xiang, Yin, Yin, Guizhi, Lu, Yi, Shi, Ludong, Dong, Jian, Shen, Chengxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885396/
https://www.ncbi.nlm.nih.gov/pubmed/29765986
http://dx.doi.org/10.1155/2018/2527406

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