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Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling
OBJECTIVE: Increased monocytes, particularly the inflammatory subset, are associated with accelerated atherosclerosis in diabetes through thus far incompletely defined mechanisms. The present study tested the hypothesis that advanced glycation end products (AGEs) promote bone marrow monocytes to pro...
Autores principales: | Jin, Xian, Liu, Liang, Zhang, Yaping, Xiang, Yin, Yin, Guizhi, Lu, Yi, Shi, Ludong, Dong, Jian, Shen, Chengxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885396/ https://www.ncbi.nlm.nih.gov/pubmed/29765986 http://dx.doi.org/10.1155/2018/2527406 |
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