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Edaravone Improves Septic Cardiac Function by Inducing an HIF-1α/HO-1 Pathway

Septic myocardial dysfunction remains prevalent and raises mortality rate in patients with sepsis. During sepsis, tissues undergo tremendous oxidative stress which contributes critically to organ dysfunction. Edaravone, a potent radical scavenger, has been proved beneficial in ischemic injuries invo...

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Detalles Bibliográficos
Autores principales: He, Chao, Zhang, Wei, Li, Suobei, Ruan, Wei, Xu, Junmei, Xiao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885492/
https://www.ncbi.nlm.nih.gov/pubmed/29765498
http://dx.doi.org/10.1155/2018/5216383

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