Genetic and pharmacological correction of aberrant dopamine synthesis using patient iPSCs with BH4 metabolism disorders

Dopamine (DA) is a neurotransmitter in the brain, playing a central role in several disease conditions, including tetrahydrobiopterin (BH4) metabolism disorders and Parkinson’s disease (PD). BH4 metabolism disorders present a variety of clinical manifestations including motor disturbance via altered...

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Detalles Bibliográficos
Autores principales: Ishikawa, Taizo, Imamura, Keiko, Kondo, Takayuki, Koshiba, Yasushi, Hara, Satoshi, Ichinose, Hiroshi, Furujo, Mahoko, Kinoshita, Masako, Oeda, Tomoko, Takahashi, Jun, Takahashi, Ryosuke, Inoue, Haruhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886044/
https://www.ncbi.nlm.nih.gov/pubmed/27798097
http://dx.doi.org/10.1093/hmg/ddw339

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