Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T-cell model system

T-cell acute lymphoblastic leukemia (T-ALL) is caused by the accumulation of multiple mutations combined with the ectopic expression of transcription factors in developing T cells. However, the molecular basis underlying cooperation between transcription factor expression and additional oncogenic mu...

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Detalles Bibliográficos
Autores principales: Bornschein, S, Demeyer, S, Stirparo, R, Gielen, O, Vicente, C, Geerdens, E, Ghesquière, B, Aerts, S, Cools, J, de Bock, C E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886055/
https://www.ncbi.nlm.nih.gov/pubmed/29151585
http://dx.doi.org/10.1038/leu.2017.328

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