The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle

Elevated blood pressure (BP) is a major global risk factor for cardiovascular disease. Genome-wide association studies have identified several genetic variants at the NPR3 locus associated with BP, but the functional impact of these variants remains to be determined. Here we confirmed, by a genome-w...

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Detalles Bibliográficos
Autores principales: Ren, Meixia, Ng, Fu Liang, Warren, Helen R, Witkowska, Kate, Baron, Michael, Jia, Zhilong, Cabrera, Claudia, Zhang, Ruoxin, Mifsud, Borbala, Munroe, Patricia B, Xiao, Qingzhong, Townsend-Nicholson, Andrea, Hobbs, Adrian J, Ye, Shu, Caulfield, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886068/
https://www.ncbi.nlm.nih.gov/pubmed/29040610
http://dx.doi.org/10.1093/hmg/ddx375

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