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The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia
The E3 ubiquitin ligase (E3) WWP1 is an oncogenic factor implicated in the maintenance of different types of epithelial cancers. The role of WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) in haematological neoplasms remains unknown. Acute myeloid leukaemia (AML) is characterized by the ex...
Autores principales: | Sanarico, A G, Ronchini, C, Croce, A, Memmi, E M, Cammarata, U A, De Antoni, A, Lavorgna, S, Divona, M, Giacò, L, Melloni, G E M, Brendolan, A, Simonetti, G, Martinelli, G, Mancuso, P, Bertolini, F, Coco, F Lo, Melino, G, Pelicci, P G, Bernassola, F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886071/ https://www.ncbi.nlm.nih.gov/pubmed/29209041 http://dx.doi.org/10.1038/leu.2017.342 |
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