COPD GWAS variant at 19q13.2 in relation with DNA methylation and gene expression

Chronic obstructive pulmonary disease (COPD) is among the major health burdens in adults. While cigarette smoking is the leading risk factor, a growing number of genetic variations have been discovered to influence disease susceptibility. Epigenetic modifications may mediate the response of the geno...

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Detalles Bibliográficos
Autores principales: Nedeljkovic, Ivana, Lahousse, Lies, Carnero-Montoro, Elena, Faiz, Alen, Vonk, Judith M, de Jong, Kim, van der Plaat, Diana A, van Diemen, Cleo C, van den Berge, Maarten, Obeidat, Ma’en, Bossé, Yohan, Nickle, David C, Consortium, B I O S, Uitterlinden, Andre G, van Meurs, Joyce B J, Stricker, Bruno H C, Brusselle, Guy G, Postma, Dirkje S, Boezen, H Marike, van Duijn, Cornelia M, Amin, Najaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886099/
https://www.ncbi.nlm.nih.gov/pubmed/29092026
http://dx.doi.org/10.1093/hmg/ddx390

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