The chaperone activity of 4PBA ameliorates the skeletal phenotype of Chihuahua, a zebrafish model for dominant osteogenesis imperfecta

Classical osteogenesis imperfecta (OI) is a bone disease caused by type I collagen mutations and characterized by bone fragility, frequent fractures in absence of trauma and growth deficiency. No definitive cure is available for OI and to develop novel drug therapies, taking advantage of a repositio...

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Detalles Bibliográficos
Autores principales: Gioia, Roberta, Tonelli, Francesca, Ceppi, Ilaria, Biggiogera, Marco, Leikin, Sergey, Fisher, Shannon, Tenedini, Elena, Yorgan, Timur A., Schinke, Thorsten, Tian, Kun, Schwartz, Jean-Marc, Forte, Fabiana, Wagener, Raimund, Villani, Simona, Rossi, Antonio, Forlino, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886106/
https://www.ncbi.nlm.nih.gov/pubmed/28475764
http://dx.doi.org/10.1093/hmg/ddx171

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