Deep molecular phenotypes link complex disorders and physiological insult to CpG methylation

Epigenetic regulation of cellular function provides a mechanism for rapid organismal adaptation to changes in health, lifestyle and environment. Associations of cytosine-guanine di-nucleotide (CpG) methylation with clinical endpoints that overlap with metabolic phenotypes suggest a regulatory role f...

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Detalles Bibliográficos
Autores principales: Zaghlool, Shaza B, Mook-Kanamori, Dennis O, Kader, Sara, Stephan, Nisha, Halama, Anna, Engelke, Rudolf, Sarwath, Hina, Al-Dous, Eman K, Mohamoud, Yasmin A, Roemisch-Margl, Werner, Adamski, Jerzy, Kastenmüller, Gabi, Friedrich, Nele, Visconti, Alessia, Tsai, Pei-Chien, Spector, Tim, Bell, Jordana T, Falchi, Mario, Wahl, Annika, Waldenberger, Melanie, Peters, Annette, Gieger, Christian, Pezer, Marija, Lauc, Gordan, Graumann, Johannes, Malek, Joel A, Suhre, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Association Studies Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886112/
https://www.ncbi.nlm.nih.gov/pubmed/29325019
http://dx.doi.org/10.1093/hmg/ddy006

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