Clinical outcome of concomitant vs interrupted BRAF inhibitor therapy during radiotherapy in melanoma patients

BACKGROUND: Concomitant radiation with BRAF inhibitor (BRAFi) therapy may increase radiation-induced side effects but also potentially improve tumour control in melanoma patients. METHODS: A total of 155 patients with BRAF-mutated melanoma from 17 European skin cancer centres were retrospectively an...

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Detalles Bibliográficos
Autores principales: Hecht, Markus, Meier, Friedegund, Zimmer, Lisa, Polat, Bülent, Loquai, Carmen, Weishaupt, Carsten, Forschner, Andrea, Gutzmer, Ralf, Utikal, Jochen S, Goldinger, Simone M, Geier, Michael, Hassel, Jessica C, Balermpas, Panagiotis, Kiecker, Felix, Rauschenberg, Ricarda, Dietrich, Ursula, Clemens, Patrick, Berking, Carola, Grabenbauer, Gerhard, Schadendorf, Dirk, Grabbe, Stephan, Schuler, Gerold, Fietkau, Rainer, Distel, Luitpold V, Heinzerling, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886123/
https://www.ncbi.nlm.nih.gov/pubmed/29438368
http://dx.doi.org/10.1038/bjc.2017.489

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