PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC

BACKGROUND: PD-L1 expression in tumour tissues is widely used to select patients to receive anti-PD-1/PD-L1 antibodies, but data are lacking on the correlation of plasma PD-L1 levels with the effect of treatments. METHODS: To investigate the association between PD-L1 mRNA in plasma-derived exosomes...

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Detalles Bibliográficos
Autores principales: Del Re, Marzia, Marconcini, Riccardo, Pasquini, Giulia, Rofi, Eleonora, Vivaldi, Caterina, Bloise, Francesco, Restante, Giuliana, Arrigoni, Elena, Caparello, Chiara, Bianco, Maria Grazia, Crucitta, Stefania, Petrini, Iacopo, Vasile, Enrico, Falcone, Alfredo, Danesi, Romano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886129/
https://www.ncbi.nlm.nih.gov/pubmed/29509748
http://dx.doi.org/10.1038/bjc.2018.9

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