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Loss of p300 and CBP disrupts histone acetylation at the mouse Sry promoter and causes XY gonadal sex reversal

CREB-binding protein (CBP, CREBBP, KAT3A) and its closely related paralogue p300 (EP300, KAT3B), together termed p300/CBP, are histone/lysine acetyl-transferases that control gene expression by modifying chromatin-associated proteins. Here, we report roles for both of these chromatin-modifying enzym...

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Detalles Bibliográficos
Autores principales:	Carré, Gwenn-Aël, Siggers, Pam, Xipolita, Marilena, Brindle, Paul, Lutz, Beat, Wells, Sara, Greenfield, Andy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886154/ https://www.ncbi.nlm.nih.gov/pubmed/29145650 http://dx.doi.org/10.1093/hmg/ddx398

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