Cargando…

In vitro characterization of mitochondrial function and structure in rat and human cells with a deficiency of the NADH: ubiquinone oxidoreductase Ndufc2 subunit

Ndufc2, a subunit of the NADH: ubiquinone oxidoreductase, plays a key role in the assembly and activity of complex I within the mitochondrial OXPHOS chain. Its deficiency has been shown to be involved in diabetes, cancer and stroke. To improve our knowledge on the mechanisms underlying the increased...

Descripción completa

Detalles Bibliográficos
Autores principales: Raffa, Salvatore, Scrofani, Cristina, Valente, Sabatino, Micaloni, Andrea, Forte, Maurizio, Bianchi, Franca, Coluccia, Roberta, Geurts, Aron M, Sciarretta, Sebastiano, Volpe, Massimo, Torrisi, Maria Rosaria, Rubattu, Speranza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886163/
https://www.ncbi.nlm.nih.gov/pubmed/28973657
http://dx.doi.org/10.1093/hmg/ddx333