Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function

Fragile X Syndrome (FXS), the most prevalent form of inherited intellectual disability and the foremost monogenetic cause of autism, is caused by loss of expression of the FMR1 gene . Here, we show that dfmr1 modulates the global metabolome in Drosophila. Despite our previous discovery of increased...

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Detalles Bibliográficos
Autores principales: Weisz, Eliana D, Towheed, Atif, Monyak, Rachel E, Toth, Meridith S, Wallace, Douglas C, Jongens, Thomas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886180/
https://www.ncbi.nlm.nih.gov/pubmed/29106525
http://dx.doi.org/10.1093/hmg/ddx387

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