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Rescue of hyperexcitability in hippocampal CA1 neurons from Mecp2 ((-/y)) mouse through surface potential neutralization

Hyperventilation is a known feature of Rett syndrome (RTT). However, how hyperventilation is related to other RTT symptoms such as hyperexcitability is unknown. Intense breathing during hyperventilation induces hypocapnia and culminates in respiratory alkalosis. Alkalinization of extracellular milie...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Saju, Mironov, Sergej L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886422/
https://www.ncbi.nlm.nih.gov/pubmed/29621262
http://dx.doi.org/10.1371/journal.pone.0195094