Molecular evolution of DNMT1 in vertebrates: Duplications in marsupials followed by positive selection

DNA methylation is mediated by a conserved family of DNA methyltransferases (Dnmts). The human genome encodes three active Dnmts (Dnmt1, Dnmt3a and Dnmt3b), the tRNA methyltransferase Dnmt2, and the regulatory protein Dnmt3L. Despite their high degree of conservation among different species, genes e...

Descripción completa

Detalles Bibliográficos
Autores principales: Alvarez-Ponce, David, Torres-Sánchez, María, Feyertag, Felix, Kulkarni, Asmita, Nappi, Taylen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886458/
https://www.ncbi.nlm.nih.gov/pubmed/29621315
http://dx.doi.org/10.1371/journal.pone.0195162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886458/
https://www.ncbi.nlm.nih.gov/pubmed/29621315
http://dx.doi.org/10.1371/journal.pone.0195162

Ejemplares similares