Cargando…

Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation

Mostrar otras versiones (1)

BACKGROUND: Smad3 linker phosphorylation plays essential roles in tumor progression and metastasis. We have previously reported that the mutation of Smad3 linker phosphorylation sites (Smad3-Erk/Pro-directed kinase site mutant constructs [EPSM]) markedly reduced the tumor progression while increasin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Sujin, Yang, Kyung-Min, Park, Yuna, Hong, Eunji, Hong, Chang Pyo, Park, Jinah, Pang, Kyoungwha, Lee, Jihee, Park, Bora, Lee, Siyoung, An, Haein, Kwak, Mi-Kyung, Kim, Junil, Kang, Jin Muk, Kim, Pyunggang, Xiao, Yang, Nie, Guangjun, Ooshima, Akira, Kim, Seong-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Cancer Prevention 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886489/ https://www.ncbi.nlm.nih.gov/pubmed/29629343 http://dx.doi.org/10.15430/JCP.2018.23.1.1

Ejemplares similares

Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation
por: Park, Sujin, et al.
Publicado: (2018)

Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells
por: An, Haein, et al.
Publicado: (2021)

Degradation of DRAK1 by CUL3/SPOP E3 Ubiquitin ligase promotes tumor growth of paclitaxel-resistant cervical cancer cells
por: Pang, Kyoungwha, et al.
Publicado: (2022)

Inhibition of TGF-β signalling in combination with nal-IRI plus 5-Fluorouracil/Leucovorin suppresses invasion and prolongs survival in pancreatic tumour mouse models
por: Hong, Eunji, et al.
Publicado: (2020)

ESRP1-regulated isoform switching of LRRFIP2 determines metastasis of gastric cancer
por: Lee, Jihee, et al.
Publicado: (2022)

Phosphorylation status at Smad3 linker region modulates transforming growth factor‐β‐induced epithelial‐mesenchymal transition and cancer progression
por: Ooshima, Akira, et al.
Publicado: (2019)

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers
por: Pang, Kyoungwha, et al.
Publicado: (2019)

Combination treatment of T1-44, a PRMT5 inhibitor with Vactosertib, an inhibitor of TGF-β signaling, inhibits invasion and prolongs survival in a mouse model of pancreatic tumors
por: Hong, Eunji, et al.
Publicado: (2023)

N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer
por: Yun, Rebecca, et al.
Publicado: (2023)

Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling
por: Park, Jinah, et al.
Publicado: (2013)

Differential Tissue-specific and Pathway-specific Anti-obesity Effects of Green Tea and Taeumjowitang, a Traditional Korean Medicine, in Mice
por: Kim, Junil, et al.
Publicado: (2017)

MAST4 controls cell cycle in spermatogonial stem cells
por: Lee, Seung‐Jun, et al.
Publicado: (2023)

Mast4 determines the cell fate of MSCs for bone and cartilage development
por: Kim, Pyunggang, et al.
Publicado: (2022)

The proinflammatory LTB(4)/BLT1 signal axis confers resistance to TGF-β1-induced growth inhibition by targeting Smad3 linker region
por: Jeon, Woo-Kwang, et al.
Publicado: (2015)

Sirtuin 3 Activation by Honokiol Decreases Unilateral Ureteral Obstruction-Induced Renal Inflammation and Fibrosis via Regulation of Mitochondrial Dynamics and the Renal NF-κB-TGF-β1/Smad Signaling Pathway
por: Quan, Yi, et al.
Publicado: (2020)

Dipeptide species regulate p38MAPK–Smad3 signalling to maintain chronic myelogenous leukaemia stem cells
por: Naka, Kazuhito, et al.
Publicado: (2015)

Altered Low Frequency Heart Rate Variability Associated with Agoraphobia in Panic Disorder: A Retrospective Study
por: Kim, Minjung, et al.
Publicado: (2023)

Schisandrol B and schisandrin B inhibit TGFβ1-mediated NF-κB activation via a Smad-independent mechanism
por: Chun, Jung Nyeo, et al.
Publicado: (2017)

Long-wave infrared transparent sulfur polymers enabled by symmetric thiol cross-linker
por: Lee, Miyeon, et al.
Publicado: (2023)

A novel SMAD6 variant in a patient with severely calcified bicuspid aortic valve and thoracic aortic aneurysm
por: Park, Jong Eun, et al.
Publicado: (2019)

Assessments of the In Vitro and In Vivo Linker Stability and Catabolic Fate for the Ortho Hydroxy-Protected Aryl Sulfate Linker by Immuno-Affinity Capture Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometric Assay
por: Lee, Byeong ill, et al.
Publicado: (2021)

Reducing the energy cost of running using a lightweight, low-profile elastic exosuit
por: Yang, Jaeha, et al.
Publicado: (2021)

SUMO Proteins are not Involved in TGF-β1-induced, Smad3/4-mediated Germline α Transcription, but PIASy Suppresses it in CH12F3-2A B Cells
por: Lee, Sang-Hoon, et al.
Publicado: (2014)

Pomolic Acid Ameliorates Fibroblast Activation and Renal Interstitial Fibrosis through Inhibition of SMAD-STAT Signaling Pathways
por: Park, Ji-Hyun, et al.
Publicado: (2018)

Unsupervised Fault Detection on Unmanned Aerial Vehicles: Encoding and Thresholding Approach †
por: Park, Kyung Ho, et al.
Publicado: (2021)

The association between occupational factors, depression, and health-related quality of life in military women in the Republic of Korea: a cross-sectional study
por: Kwon, Eunji, et al.
Publicado: (2021)

Metabolic and Transcriptomic Signatures of the Acute Psychological Stress Response in the Mouse Brain
por: Lee, Haein, et al.
Publicado: (2023)

TGF-Beta Induced Erk Phosphorylation of Smad Linker Region Regulates Smad Signaling
por: Hough, Chris, et al.
Publicado: (2012)

Interfacial modification in perovskite-based tandem solar cells
por: Park, Ik Jae, et al.
Publicado: (2023)

Association Between Body Mass Index and Cognitive Function in Mild Cognitive Impairment Regardless of APOE ε4 Status
por: Mun, Ye Sol, et al.
Publicado: (2022)

The Band-Importance Function for the Korean Standard Sentence Lists for Adults
por: Jin, In-Ki, et al.
Publicado: (2016)

Left atrial remodeling and mechanical dysfunction in hypertrophic cardiomyopathy
por: Kim, Kyung-Jin, et al.
Publicado: (2016)

A human-machine collaborative approach measures economic development using satellite imagery
por: Ahn, Donghyun, et al.
Publicado: (2023)

A Reciprocal Role of the Smad4‐Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells
por: Park, Jin Seok, et al.
Publicado: (2018)

Relationship between Three-Dimensional Steel Fiber Statistics and Electromagnetic Shielding Effectiveness of High-Performance, Fiber-Reinforced Cementitious Composites
por: Lee, Namkon, et al.
Publicado: (2020)

Antifibrotic Effect of Smad Decoy Oligodeoxynucleotide in a CCl(4)-Induced Hepatic Fibrosis Animal Model
por: Gwon, Mi-Gyeong, et al.
Publicado: (2018)

Serosal Cavities Contain Two Populations of Innate-like Integrin α4(high)CD4(+) T Cells, Integrin α4β1(+)α6β1(+)α4β7(−) and α4β1(+)α6β1(−)α4β7(+) Cells
por: Yang, Jeong In, et al.
Publicado: (2017)

Deletion of IP6K1 in mice accelerates tumor growth by dysregulating the tumor-immune microenvironment
por: Lee, Haein, et al.
Publicado: (2022)

Simultaneous fabrication of line and dot dual nanopatterns using miktoarm block copolymer with photocleavable linker
por: Choi, Chungryong, et al.
Publicado: (2017)

Toll/IL-1 domain-containing adaptor inducing IFN-β (TRIF) mediates innate immune responses in murine peritoneal mesothelial cells through TLR3 and TLR4 stimulation
por: Hwang, Eun-Ha, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_9i9aujca7qdaie20nsuddoer9n