Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation

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BACKGROUND: Smad3 linker phosphorylation plays essential roles in tumor progression and metastasis. We have previously reported that the mutation of Smad3 linker phosphorylation sites (Smad3-Erk/Pro-directed kinase site mutant constructs [EPSM]) markedly reduced the tumor progression while increasin...

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Detalles Bibliográficos
Autores principales: Park, Sujin, Yang, Kyung-Min, Park, Yuna, Hong, Eunji, Hong, Chang Pyo, Park, Jinah, Pang, Kyoungwha, Lee, Jihee, Park, Bora, Lee, Siyoung, An, Haein, Kwak, Mi-Kyung, Kim, Junil, Kang, Jin Muk, Kim, Pyunggang, Xiao, Yang, Nie, Guangjun, Ooshima, Akira, Kim, Seong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886489/
https://www.ncbi.nlm.nih.gov/pubmed/29629343
http://dx.doi.org/10.15430/JCP.2018.23.1.1
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