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Sildenafil ameliorates right ventricular early molecular derangement during left ventricular pressure overload

Right ventricular (RV) dysfunction following left ventricular (LV) failure is associated with poor prognosis. RV remodeling is thought initiated by the increase in the afterload of RV due to secondary pulmonary hypertension (PH) to impaired LV function; however, RV molecular changes might occur in e...

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Detalles Bibliográficos
Autores principales: Imai, Yousuke, Kariya, Taro, Iwakiri, Masaki, Yamada, Yoshitsugu, Takimoto, Eiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886579/
https://www.ncbi.nlm.nih.gov/pubmed/29621314
http://dx.doi.org/10.1371/journal.pone.0195528