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Sildenafil ameliorates right ventricular early molecular derangement during left ventricular pressure overload
Right ventricular (RV) dysfunction following left ventricular (LV) failure is associated with poor prognosis. RV remodeling is thought initiated by the increase in the afterload of RV due to secondary pulmonary hypertension (PH) to impaired LV function; however, RV molecular changes might occur in e...
Autores principales: | Imai, Yousuke, Kariya, Taro, Iwakiri, Masaki, Yamada, Yoshitsugu, Takimoto, Eiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886579/ https://www.ncbi.nlm.nih.gov/pubmed/29621314 http://dx.doi.org/10.1371/journal.pone.0195528 |
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