Clarithromycin expands CD11b(+)Gr-1(+) cells via the STAT3/Bv8 axis to ameliorate lethal endotoxic shock and post-influenza bacterial pneumonia

Macrolides are used to treat various inflammatory diseases owing to their immunomodulatory properties; however, little is known about their precise mechanism of action. In this study, we investigated the functional significance of the expansion of myeloid-derived suppressor cell (MDSC)-like CD11b(+)...

Descripción completa

Detalles Bibliográficos
Autores principales: Namkoong, Ho, Ishii, Makoto, Fujii, Hideki, Yagi, Kazuma, Asami, Takahiro, Asakura, Takanori, Suzuki, Shoji, Hegab, Ahmed E., Kamata, Hirofumi, Tasaka, Sadatomo, Atarashi, Koji, Nakamoto, Nobuhiro, Iwata, Satoshi, Honda, Kenya, Kanai, Takanori, Hasegawa, Naoki, Koyasu, Shigeo, Betsuyaku, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886688/
https://www.ncbi.nlm.nih.gov/pubmed/29621339
http://dx.doi.org/10.1371/journal.ppat.1006955

Ejemplares similares

Ejemplares similares