Streptococcal M protein promotes IL-10 production by cGAS-independent activation of the STING signaling pathway

From an evolutionary point of view a pathogen might benefit from regulating the inflammatory response, both in order to facilitate establishment of colonization and to avoid life-threatening host manifestations, such as septic shock. In agreement with this notion Streptococcus pyogenes exploits type...

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Detalles Bibliográficos
Autores principales: Movert, Elin, Lienard, Julia, Valfridsson, Christine, Nordström, Therése, Johansson-Lindbom, Bengt, Carlsson, Fredric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886698/
https://www.ncbi.nlm.nih.gov/pubmed/29579113
http://dx.doi.org/10.1371/journal.ppat.1006969

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