SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity

Chondrocytes and osteoblasts differentiate from a common mesenchymal precursor, the osteochondroprogenitor (OCP), and help build the vertebrate skeleton. The signaling pathways that control lineage commitment for OCPs are incompletely understood. We asked whether the ubiquitously expressed protein-t...

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Detalles Bibliográficos
Autores principales: Zuo, Chunlin, Wang, Lijun, Kamalesh, Raghavendra M., Bowen, Margot E., Moore, Douglas C., Dooner, Mark S., Reginato, Anthony M., Wu, Qian, Schorl, Christoph, Song, Yueming, Warman, Matthew L., Neel, Benjamin G., Ehrlich, Michael G., Yang, Wentian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886981/
https://www.ncbi.nlm.nih.gov/pubmed/29644115
http://dx.doi.org/10.1038/s41413-018-0013-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886981/
https://www.ncbi.nlm.nih.gov/pubmed/29644115
http://dx.doi.org/10.1038/s41413-018-0013-z

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